Gender is changing!!!

                      Gender is changing!!!

That is, a set of medical procedures undergone by transgender people to alter their sexual characteristics from male to female or from female to male. Several medical conditions can result in a natural sex change in humans, where the appearance at birth is somewhat, mostly, or completely of one sex, but changes over the course of a lifetime to being somewhat, mostly or completely of the other sex. The overwhelming majority of natural sex changes are from a female appearance at birth to a male appearance after puberty; due to either 5-alpha-reductase deficiency (5alpha-RD-2) or 17-beta-hydroxysteroid dehydrogenise deficiency (17beta-HSD-3). A relative handful of male to female changes have been reported, and the etiologist of these are not well understood.

She was he!!!

Genetic females (with two X chromosomes) with congenital adrenal hyperplasia lack an enzyme needed by the adrenal gland to make the hormones cortical and aldosterone. Without these hormones, the body produces more androgen, a type of male sex hormone. This causes male characteristics to appear early (or inappropriately).

Genetic males (with one X and one Y chromosome) with androgen insensitivity syndrome are resistant to male hormone androgen. As a result, the person has some or all of the physical characteristics of a woman, despite having the genetic makeup of a man. The degree of sexual ambiguity varies widely in persons with incomplete AIS. Incomplete AIS can include other disorders such as Reifenstein syndrome which is associated with breast development.