Lesson 1
Actually our scientists are still unable to give proper
description about the working process of BRAIN.
The human brain is perhaps the most complex of organs,
boasting between 50-100 billion nerve cells or neurons that constantly interact
with each other. These neurons ‘carry’ messages through electrochemical
processes; meaning, chemicals in our body (charged sodium, potassium and
chloride ions) move in and out of these cells and establish an electrical
current.
Rodrigo Quian Quiroga Professor of Leicester Bioengineer
University publish an article called Nature
Reviews Neuroscience. In the article, Prof. Quian Quiroga and co-author Dr.
Stefano Panzeri discuss new methodologies that are enabling scientists to
better understand how our brain processes information.
“The human brain typically makes decisions based on a single
stimulus, by evaluating the activity of a large number of neurons. I don’t get
in front of a tiger 100 times to make an average of my neuronal responses and
decide if I should run or not. If I see a tiger once, I run” said by Prof.
Quian Quiroga
He also add
“A major challenge of our days is (thus) to develop the
methodologies to record and process the data from hundreds of neurons and
developing these is by no means a trivial task”.
“Our brains are able to create
very complex processes – just imagine the perfect harmony
with which we move different muscles for normal walking – thousands of neurons
are involved in this and to determine the role of each is complicated”.
In review paper he discusses about two things. One is ‘decoding’
and ‘information theory’.
‘Decoding’ essentially helps determine what must have caused
a particular response (much like “working backwards”). Thus, the response of a
neuronal population is used to reconstruct the stimulus or behaviour that
caused it in the first place. ‘Information theory’, on the other hand,
literally quantifies how much information a number of neurons carry about the
stimulus.
He said “together, the two approaches not only allow
scientists to extract more information on how the brain works, but information
that is ambiguous at the level of single neurons, can be clearly evaluated when
the whole ‘population’ is considered”
The review is an asset for anyone involved in the field, as
it carefully considers and evaluates the two statistical approaches, as well as
describes potential applications.